速看！12月明星蛋白清單，高效科研之選
本期云克隆精選重組蛋白、活性蛋白、熱門靶點(diǎn)蛋白三大核心品類，全面覆蓋分子互作分析、細(xì)胞功能實(shí)驗(yàn)、藥物高通量篩選等關(guān)鍵研究場(chǎng)景，為你的科研項(xiàng)目提供精準(zhǔn)支撐。所有產(chǎn)品均遵循頂刊同款制備配方，或經(jīng)權(quán)威實(shí)驗(yàn)室多輪嚴(yán)格驗(yàn)證，溯源可查、數(shù)據(jù)精準(zhǔn)，從源頭規(guī)避實(shí)驗(yàn)變量。
選擇云克隆優(yōu)質(zhì)蛋白，幫你跳過反復(fù)試錯(cuò)的耗時(shí)環(huán)節(jié)，降低實(shí)驗(yàn)不確定性，讓科研進(jìn)程更高效、成果產(chǎn)出更穩(wěn)健，加速論文發(fā)表之路。云克隆愿以可靠品質(zhì)，陪伴每一位科研人，穩(wěn)步探索生命科學(xué)的未知疆界。
01 ADM
產(chǎn)品貨號(hào)：APA220Mu01
產(chǎn)品名稱：腎上腺髓質(zhì)素(ADM)活性蛋白
文獻(xiàn)名稱：METTL14 integrates tumor-derived SAM to drive parabrachial epigenetic rewiring in pancreatic cancer
雜志名稱：Neuron
影響因子：15.0
PMID/DOI：10.1016/j.neuron.2025.10.002
發(fā)表日期： 11/1/2025
發(fā)表單位：中國廣東省廣州市腫瘤防治中心中山大學(xué)腫瘤防治中心麻醉科
樣本類型：小鼠外側(cè)臂旁核谷氨酸能神經(jīng)元（LPBN）
應(yīng)用類型：細(xì)胞培養(yǎng)
METTL14-mediated m6A modification drives comorbidity via ADM in LPBN glutamatergic neurons(E) LPBN Adm mRNA expression (n = 7). (F) ADM protein levels in the LPBN (n = 10). (H) MeRIP-qPCR measuring m6A levels on Adm mRNA in LPBN (n = 4).
02 CX3CL1
產(chǎn)品貨號(hào)：APA040Hu01
產(chǎn)品名稱：趨化因子C-X3-C-基元配體1(CX3CL1)活性蛋白
文獻(xiàn)名稱：Heat Stress Modulates WDR5‐Mediated H3K4me3 Modification to Induce Melanogenesis via Activating CX3CL1/CX3CR1 Axis
雜志名稱：Advanced Science
影響因子：14.1
PMID/DOI：41267387
發(fā)表日期： 11/20/2025
發(fā)表單位：中南大學(xué)湘雅三醫(yī)院皮膚科,中南大學(xué)湘雅二醫(yī)院臨床研究中心
樣本類型：人黑色素原代細(xì)胞（MC）、人黑色素瘤細(xì)胞（MNT1）
應(yīng)用類型：細(xì)胞培養(yǎng)
CX3CL1 can promote melanogenesis. a,b) MNT1 or MC cells were treated with α-MSH or CX3CL1: after 24 h, the melanin content in the cells was detected by Fontana-Masson staining (scale =20 μm), and quantitative analysis was performed using ImageJ (a);
03 ITGb3
產(chǎn)品貨號(hào)：RPD353Mu01
產(chǎn)品名稱：Slit同源物3(Slit3)重組蛋白
文獻(xiàn)名稱：Osteoclast‐Derived SLIT3 Mediates Osteoarthritis Pain and Degenerative Changes
雜志名稱：Advanced Science
影響因子：14.1
PMID/DOI：41255240
發(fā)表日期： 11/19/2025
發(fā)表單位：中國空軍軍醫(yī)大學(xué)唐都醫(yī)院口腔科/口腔頜面重建與再生全國重點(diǎn)實(shí)驗(yàn)室
樣本類型：小鼠三叉神經(jīng)節(jié)細(xì)胞（TG）
應(yīng)用類型：細(xì)胞培養(yǎng)
To further verify the role of osteoclasts, we added 500 μg mL?1 SLIT3 protein to the co-culture medium in vitro, which significantly promoted the growth of sensory neuron axons (Figure 6f–h).
Figure6 f) Quantitative analysis in panel (h). n = 6. g) Schematic diagram for extracting trigeminal ganglion (TG) cells. h) Representative microscopy images of TG cells after different treatments.